Do NOT use Renagel if:

• you are allergic to any ingredient in Renagel
• you have low blood phosphate levels or a blockage of your bowels.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Renagel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have difficulty swallowing or certain stomach or bowel problems (eg, severe constipation), or if you have had major stomach or bowel surgery
• if you take medicines for irregular heartbeat, seizures, or thyroid problems.

Some medicines may interact with Renagel. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Ciprofloxacin because its effectiveness may be decreased by Renagel.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Renagel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

• Renagel may reduce certain vitamins in your body. Check with your doctor about whether or not you should take a vitamin supplement while you take Renagel.
• Follow the diet program given to you by your health care provider.
• Lab tests, including calcium, bicarbonate, and chloride blood levels, may be performed while you use Renagel. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Renagel should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
• Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Renagel while you are pregnant. It is not known if Renagel is found in breast milk. If you are or will be breast-feeding while you use Renagel, check with your doctor. Discuss any possible risks to your baby.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Constipation; diarrhea; gas; indigestion; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent constipation or stomach pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects.